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Transforming Growth Factor-β1 Induces the Differentiation of Myogenic Cells into Fibrotic Cells in Injured Skeletal Muscle : A Key Event in Muscle Fibrogenesis
Transforming growth factor-β1 (TGF-β1) is thought to play a crucial role in fibrotic diseases. This study demonstrates for the first time that TGF-β1 stimulation can induce myoblasts (C2C12 cells) to express TGF-β1 in an autocrine manner, down-regulate the expression of myogenic proteins, and initia...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Investigative Pathology
2004
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1614716/ https://ncbi.nlm.nih.gov/pubmed/14982854 |
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