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Sequential Unfolding of Individual Helices of Bacterioopsin Observed in Molecular Dynamics Simulations of Extraction from the Purple Membrane

Multiple molecular dynamics simulations of bacterioopsin pulling from its C-terminus show that its α-helices unfold individually. In the first metastable state observed in the simulations, helix G is unfolded at its C-terminal segment while the rest of helix G (residues 200–216) is folded and oppose...

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Detalhes bibliográficos
Main Authors: Seeber, Michele, Fanelli, Francesca, Paci, Emanuele, Caflisch, Amedeo
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1614499/
https://ncbi.nlm.nih.gov/pubmed/16861280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.088591
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