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Arginase: marker, effector, or candidate gene for asthma?
Microarray analysis of the expression profiles of lung tissue in two murine models of asthma revealed high levels of arginase I and arginase II activity, in association with IL-4 and IL-13 overexpression, suggesting that arginine pathways are critical in the pathogenesis of asthma.
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| Autor principal: | |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
2003
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC161429/ https://ncbi.nlm.nih.gov/pubmed/12813015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200318908 |
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