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Arginase: marker, effector, or candidate gene for asthma?

Microarray analysis of the expression profiles of lung tissue in two murine models of asthma revealed high levels of arginase I and arginase II activity, in association with IL-4 and IL-13 overexpression, suggesting that arginine pathways are critical in the pathogenesis of asthma.

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Detalhes bibliográficos
Autor principal: Vercelli, Donata
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC161429/
https://ncbi.nlm.nih.gov/pubmed/12813015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200318908
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