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The Promise of Integrins as Effective Targets for Anticancer Agents

This review will briefly describe integrin function, address why integrins are attractive targets for chemotherapeutic drug design, and discuss some ongoing studies aimed at inhibiting integrin activity. Integrins are cell surface heterodimeric receptors. They modulate many cellular processes includ...

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Bibliografische gegevens
Hoofdauteurs: Rust, William L., Carper, Stephen W., Plopper, George E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2002
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC161362/
https://ncbi.nlm.nih.gov/pubmed/12488576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/S1110724302204015
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