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Silencing of Fas, but Not Caspase-8, in Lung Epithelial Cells Ameliorates Pulmonary Apoptosis, Inflammation, and Neutrophil Influx after Hemorrhagic Shock and Sepsis

Apoptosis and inflammation play an important role in the pathogenesis of direct/pulmonary acute lung injury (ALI). However, the role of the Fas receptor-driven apoptotic pathway in indirect/nonpulmonary ALI is virtually unstudied. We hypothesized that if Fas or caspase-8 plays a role in the inductio...

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Detaylı Bibliyografya
Asıl Yazarlar: Perl, Mario, Chung, Chun-Shiang, Lomas-Neira, Joanne, Rachel, Tina-Marie, Biffl, Walter L., Cioffi, William G., Ayala, Alfred
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Investigative Pathology 2005
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1613198/
https://ncbi.nlm.nih.gov/pubmed/16314469
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