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Acetanilide Oxidation in Phenylbutazone-associated Hypoplastic Anaemia

Acetanilide like phenylbutazone is paraoxidized by the liver endoplasmic reticulum as a primary biotransformation step. Both compounds were given at different times to each of 10 healthy volunteer subjects and the plasma disappearances measured. Correlation was shown between plasma clearance values...

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Detalhes bibliográficos
Main Authors: Cunningham, J. L., Leyland, M. J., Delamore, I. W., Evans, D. A. Price
Formato: Artigo
Idioma:Inglês
Publicado em: 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1611743/
https://ncbi.nlm.nih.gov/pubmed/4411815
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