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High-Level Carbapenem Resistance in a Klebsiella pneumoniae Clinical Isolate Is Due to the Combination of bla(ACT-1) β-Lactamase Production, Porin OmpK35/36 Insertional Inactivation, and Down-Regulation of the Phosphate Transport Porin PhoE

Clinical isolates of Klebsiella pneumoniae resistant to carbapenems and essentially all other antibiotics (multidrug resistant) are being isolated from some hospitals in New York City with increasing frequency. A highly related pair of K. pneumoniae strains isolated on the same day from one patient...

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Autori principali: Kaczmarek, Frank M., Dib-Hajj, Fadia, Shang, Wenchi, Gootz, Thomas D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1610099/
https://ncbi.nlm.nih.gov/pubmed/17005822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00285-06
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