Compartmentalized Intrapulmonary Pharmacokinetics of Amphotericin B and Its Lipid Formulations

We investigated the compartmentalized intrapulmonary pharmacokinetics of amphotericin B and its lipid formulations in healthy rabbits. Cohorts of three to seven noninfected, catheterized rabbits received 1 mg of amphotericin B deoxycholate (DAMB) per kg of body weight or 5 mg of either amphotericin...

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Detalhes bibliográficos
Main Authors: Groll, Andreas H., Lyman, Caron A., Petraitis, Vidmantas, Petraitiene, Ruta, Armstrong, Derek, Mickiene, Diana, Alfaro, Raul M., Schaufele, Robert L., Sein, Tin, Bacher, John, Walsh, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1610093/
https://ncbi.nlm.nih.gov/pubmed/17005824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00241-06
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