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Deletions of the Endocytic Components VPS28 and VPS32 in Candida albicans Lead to Echinocandin and Azole Hypersensitivity

Vps28p and Vps32p act in both the endocytic and the pH signaling pathways in yeasts and are required for Candida albicans virulence. Here, we show that deletions of VPS28 and VPS32 increase the susceptibility of C. albicans to cell wall disruption agents, echinocandin and azole antifungal agents.

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書誌詳細
主要な著者: Cornet, Muriel, Gaillardin, Claude, Richard, Mathias L.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2006
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1610091/
https://ncbi.nlm.nih.gov/pubmed/17005841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00391-06
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