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Pharmacokinetics and Tolerability of Daptomycin at Doses up to 12 Milligrams per Kilogram of Body Weight Once Daily in Healthy Volunteers

Daptomycin, a novel lipopeptide, is bactericidal against a broad range of gram-positive strains, including methicillin- (MRSA) and vancomycin-resistant Staphylococcus aureus. Daptomycin is approved at 4 mg/kg of body weight given intravenously once daily for the treatment of complicated skin and ski...

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Detalhes bibliográficos
Main Authors: Benvenuto, Mark, Benziger, David P., Yankelev, Sara, Vigliani, Gloria
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1610083/
https://ncbi.nlm.nih.gov/pubmed/17005801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00247-06
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