Functional analysis of a group A streptococcal glycoside hydrolase Spy1600 from family 84 reveals it is a β-N-acetylglucosaminidase and not a hyaluronidase

Group A streptococcus (Streptococcus pyogenes) is the causative agent of severe invasive infections such as necrotizing fasciitis (the so-called ‘flesh eating disease’) and toxic-shock syndrome. Spy1600, a glycoside hydrolase from family 84 of the large superfamily of glycoside hydrolases, has been...

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Bibliografiske detaljer
Main Authors: Sheldon, William L., Macauley, Matthew S., Taylor, Edward J., Robinson, Charlotte E., Charnock, Simon J., Davies, Gideon J., Vocadlo, David J., Black, Gary W.
Format: Artigo
Sprog:Inglês
Udgivet: Portland Press Ltd. 2006
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1609908/
https://ncbi.nlm.nih.gov/pubmed/16822234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060307
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