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Urocortin and Adrenomedullin Prevent Lethal Endotoxemia by Down-Regulating the Inflammatory Response

Urocortin 1 (UCN) and adrenomedullin (AM) are two neuropeptides that have emerged as potential endogenous anti-inflammatory factors based on their production by and binding to immune cells. Because human septic shock involves excessive inflammatory cytokine production, we investigated the effect of...

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Bibliographic Details
Main Authors: Gonzalez-Rey, Elena, Chorny, Alejo, Varela, Nieves, Robledo, Gema, Delgado, Mario
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606636/
https://ncbi.nlm.nih.gov/pubmed/16723707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.051104
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