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Inhibition of Platelet-Derived Growth Factor B Signaling Enhances the Efficacy of Anti-Vascular Endothelial Growth Factor Therapy in Multiple Models of Ocular Neovascularization

‘Vascular endothelial growth factor-A (VEGF-A) blockade has been recently validated as an effective strategy for the inhibition of new blood vessel growth in cancer and ocular pathologies. However, several studies have also shown that anti-VEGF therapy may not be as effective in the treatment of est...

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Autors principals: Jo, Nobuo, Mailhos, Carolina, Ju, Meihua, Cheung, Eunice, Bradley, John, Nishijima, Kazuaki, Robinson, Gregory S., Adamis, Anthony P., Shima, David T.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606616/
https://ncbi.nlm.nih.gov/pubmed/16723717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.050588
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