Expression and Oncogenic Role of Brk (PTK6/Sik) Protein Tyrosine Kinase in Lymphocytes

Tyrosine kinases play a fundamental role in cell proliferation, survival, adhesion, and motility and have also been shown to mediate malignant cell transformation. Here we describe constitutive expression of the protein tyrosine kinase Brk in a large proportion of cutaneous T-cell lymphomas and othe...

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Hlavní autoři: Kasprzycka, Monika, Majewski, Miroslaw, Wang, Zhi-Jong, Ptasznik, Andrzej, Wysocka, Maria, Zhang, Qian, Marzec, Michal, Gimotty, Phyllis, Crompton, Mark R., Wasik, Mariusz A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2006
Témata:
Original Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606578/
https://ncbi.nlm.nih.gov/pubmed/16651629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.050521
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