Thrombin-Activatable Fibrinolysis Inhibitor Deficiency Attenuates Bleomycin-Induced Lung Fibrosis

Decreased fibrinolytic function favors the development of pulmonary fibrosis. Thrombin-activatable fibrinolysis inhibitor (TAFI) is a strong suppressor of fibrinolysis, but its role in lung fibrosis is unknown. Therefore, we compared bleomycin-induced lung fibrosis in TAFI-deficient, heterozygous, a...

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Main Authors: Fujimoto, Hajime, Gabazza, Esteban C., Taguchi, Osamu, Nishii, Yoichi, Nakahara, Hiroki, Bruno, Nelson E., D’Alessandro-Gabazza, Corina N., Kasper, Michael, Yano, Yutaka, Nagashima, Mariko, Morser, John, Broze, George J., Suzuki, Koji, Adachi, Yukihiko
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2006
Teme:
Original Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606569/
https://ncbi.nlm.nih.gov/pubmed/16565485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.050610
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