Lipid Peroxidation Inhibition Blunts Nuclear Factor-κB Activation, Reduces Skeletal Muscle Degeneration, and Enhances Muscle Function in mdx Mice

Duchenne muscular dystrophy (DMD) is a progressive muscle-wasting disease resulting from lack of the sarcolemmal protein dystrophin. However, the mechanism leading to the final disease status is not fully understood. Several lines of evidence suggest a role for nuclear factor (NF)-κB in muscle degen...

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Detalhes bibliográficos
Main Authors: Messina, Sonia, Altavilla, Domenica, Aguennouz, M’hammed, Seminara, Paolo, Minutoli, Letteria, Monici, Maria C., Bitto, Alessandra, Mazzeo, Anna, Marini, Herbert, Squadrito, Francesco, Vita, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2006
Assuntos:
Original Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606515/
https://ncbi.nlm.nih.gov/pubmed/16507907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.050673
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