Autophagic Cardiomyocyte Death in Cardiomyopathic Hamsters and Its Prevention by Granulocyte Colony-Stimulating Factor

In UM-X7.1 hamster model of human dilated cardiomyopathy, heart failure progressively develops and causes 50% mortality by 30 weeks of age. Through ultrastructural analysis, we found that many cardiomyocytes of this model contain typical autophagic vacuoles including degraded mitochondria, glycogen...

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Detalhes bibliográficos
Main Authors: Miyata, Shusaku, Takemura, Genzou, Kawase, Yukinori, Li, Yiwen, Okada, Hideshi, Maruyama, Rumi, Ushikoshi, Hiroaki, Esaki, Masayasu, Kanamori, Hiromitsu, Li, Longhu, Misao, Yu, Tezuka, Asaki, Toyo-Oka, Teruhiko, Minatoguchi, Shinya, Fujiwara, Takako, Fujiwara, Hisayoshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2006
Assuntos:
Original Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606501/
https://ncbi.nlm.nih.gov/pubmed/16436654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.050137
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