Plasmin Modulates Vascular Endothelial Growth Factor-A-Mediated Angiogenesis during Wound Repair

Plasmin-catalyzed cleavage of the vascular endothelial growth factor (VEGF)-A isoform VEGF165 results in loss of its carboxyl-terminal heparin-binding domain and significant loss in its bioactivity. Little is known about the in vivo significance of this process. To investigate the biological relevan...

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Detalhes bibliográficos
Main Authors: Roth, Detlev, Piekarek, Michael, Paulsson, Mats, Christ, Hildegard, Bloch, Wilhelm, Krieg, Thomas, Davidson, Jeffrey M., Eming, Sabine A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2006
Assuntos:
Original Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606492/
https://ncbi.nlm.nih.gov/pubmed/16436680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.050372
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