Up-Regulated Expression of Zonula Occludens Protein-1 in Human Melanoma Associates with N-Cadherin and Contributes to Invasion and Adhesion

During the process of malignant transformation, nascent melanoma cells escape keratinocyte control through down-regulation of E-cadherin and instead communicate among themselves and with fibroblasts via N-cadherin-based cell-cell contacts. The zonula occludens (ZO) protein-1 is a membrane-associated...

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Bibliografiske detaljer
Main Authors: Smalley, Keiran S.M., Brafford, Patricia, Haass, Nikolas K., Brandner, Johanna M., Brown, Eric, Herlyn, Meenhard
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2005
Fag:
Original Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606406/
https://ncbi.nlm.nih.gov/pubmed/15855653
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