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Stroma-Derived Three-Dimensional Matrices Are Necessary and Sufficient to Promote Desmoplastic Differentiation of Normal Fibroblasts

Stromagenesis is a host reaction of connective tissue that, when induced in cancer, produces a progressive and permissive mesenchymal microenvironment, thereby supporting tumor progression. The stromal microenvironment is complex and comprises several cell types, including fibroblasts, the primary p...

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Autors principals: Amatangelo, Michael D., Bassi, Daniel E., Klein-Szanto, Andrés J.P., Cukierman, Edna
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1603576/
https://ncbi.nlm.nih.gov/pubmed/16049333
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