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Molecular Pathogenesis of Chronic Wounds : The Role of β-Catenin and c-myc in the Inhibition of Epithelialization and Wound Healing

Lack of understanding of the molecular mechanisms and pathogenesis of impaired healing in chronic ulcers is a serious health issue that contributes to excessive limb amputations and mortality. Here we show that β-catenin and its downstream targets in keratinocytes, c-myc, and keratins K6 and K16, pl...

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Auteurs principaux: Stojadinovic, Olivera, Brem, Harold, Vouthounis, Constantinos, Lee, Brian, Fallon, John, Stallcup, Michael, Merchant, Ankit, Galiano, Robert D., Tomic-Canic, Marjana
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2005
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1603435/
https://ncbi.nlm.nih.gov/pubmed/15972952
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