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Follicular Thyroid Tumors with the PAX8-PPARγ1 Rearrangement Display Characteristic Genetic Alterations

Follicular thyroid carcinomas (FTC) arise through oncogenic pathways distinct from those involved in the papillary histotype. Recently, a t(2;3)(q13;p25) rearrangement, which juxtaposes the thyroid transcription factor PAX8 to the peroxisome proliferator-activated receptor (PPAR) γ1, was described i...

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Autors principals: Lacroix, Ludovic, Lazar, Vladimir, Michiels, Stefan, Ripoche, Hugues, Dessen, Philippe, Talbot, Monique, Caillou, Bernard, Levillain, Jean-Pierre, Schlumberger, Martin, Bidart, Jean-Michel
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1603430/
https://ncbi.nlm.nih.gov/pubmed/15972966
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