Dual Infection with Helicobacter bilis and Helicobacter hepaticus in P-Glycoprotein-Deficient mdr1a(−/−) Mice Results in Colitis that Progresses to Dysplasia

Patients with inflammatory bowel disease (IBD) are at increased risk for developing high-grade dysplasia and colorectal cancer. Animal IBD models that develop dysplasia and neoplasia may help elucidate the link between inflammation and colorectal cancer. Mdr1a(−/−) mice lack the membrane efflux pump...

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Autors principals: Maggio-Price, Lillian, Bielefeldt-Ohmann, Helle, Treuting, Piper, Iritani, Brian M., Zeng, Weiping, Nicks, Andrea, Tsang, Mark, Shows, Donna, Morrissey, Phil, Viney, Joanne L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2005
Matèries:
Original Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602406/
https://ncbi.nlm.nih.gov/pubmed/15920164
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