Transforming Growth Factor-β and Platelet-Derived Growth Factor Signal via c-Jun N-Terminal Kinase-Dependent Smad2/3 Phosphorylation in Rat Hepatic Stellate Cells after Acute Liver Injury

After liver injury, transforming growth factor-β (TGF-β) and platelet-derived growth factor (PDGF) regulate the activation of hepatic stellate cells (HSCs) and tissue remodeling. Mechanisms of PDGF signaling in the TGF-β-triggered cascade are not completely understood. TGF-β signaling involves phosp...

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Detalhes bibliográficos
Main Authors: Yoshida, Katsunori, Matsuzaki, Koichi, Mori, Shigeo, Tahashi, Yoshiya, Yamagata, Hideo, Furukawa, Fukiko, Seki, Toshihito, Nishizawa, Mikio, Fujisawa, Junichi, Okazaki, Kazuichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2005
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Original Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602385/
https://ncbi.nlm.nih.gov/pubmed/15793284
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