Transdifferentiation of Mature Rat Hepatocytes into Bile Duct-Like Cells in Vitro

We investigated the mechanism of phenotypic plasticity of hepatocytes in a three-dimensional organoid culture system, in which hepatocytic spheroids were embedded within a collagen gel matrix. Hepatocytes expressed several bile duct markers including cytokeratin (CK) 19 soon after culture and underw...

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Bibliographic Details
Main Authors: Nishikawa, Yuji, Doi, Yuko, Watanabe, Hitoshi, Tokairin, Takuo, Omori, Yasufumi, Su, Mu, Yoshioka, Toshiaki, Enomoto, Katsuhiko
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2005
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Original Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602375/
https://ncbi.nlm.nih.gov/pubmed/15793288
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