Recombinant α2(IV)NC1 Domain Inhibits Tumor Cell-Extracellular Matrix Interactions, Induces Cellular Senescence, and Inhibits Tumor Growth in Vivo

Cellular interaction with the extracellular matrix is thought to be a critical event in controlling angiogenesis and tumor growth. In our previous studies, genetically distinct noncollagenous (NC) domains of type-IV collagen were shown to interact with integrin receptors expressed on the surface of...

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Détails bibliographiques
Auteurs principaux: Roth, Jennifer M., Akalu, Abebe, Zelmanovich, Anat, Policarpio, Desiree, Ng, Bruce, MacDonald, Shannon, Formenti, Silvia, Liebes, Leonard, Brooks, Peter C.
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2005
Sujets:
Original Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602358/
https://ncbi.nlm.nih.gov/pubmed/15743801
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