Decreased Thickness and Integrity of the Macular Elastic Layer of Bruch’s Membrane Correspond to the Distribution of Lesions Associated with Age-Related Macular Degeneration

Age-related macular degeneration (AMD) is a leading cause of blindness in the elderly. In its severest form, choroidal neovessels breach the macular Bruch’s membrane, an extracellular matrix compartment comprised of elastin and collagen laminae, and grow into the retina. We sought to determine wheth...

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Hlavní autoři: Chong, N.H. Victor, Keonin, Jason, Luthert, Phil J., Frennesson, Christina I., Weingeist, David M., Wolf, Rachel L., Mullins, Robert F., Hageman, Gregory S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2005
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Original Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602307/
https://ncbi.nlm.nih.gov/pubmed/15632016
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