Matrix Metalloproteinase-9 Knockout Confers Resistance to Corneal Epithelial Barrier Disruption in Experimental Dry Eye

Altered corneal epithelial barrier function is the cause for ocular irritation and visual morbidity in dry eye disease. Increased matrix metalloproteinase (MMP)-9 activity has been observed in the tear fluid of dry eye patients. To determine the pathogenic role of MMP-9 in the corneal epithelial dis...

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Hauptverfasser: Pflugfelder, Stephen C., Farley, William, Luo, Lihui, Chen, Lucy Zhuo, de Paiva, Cintia S., Olmos, Lisa C., Li, De-Quan, Fini, M. Elizabeth
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2005
Schlagworte:
Original Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602302/
https://ncbi.nlm.nih.gov/pubmed/15632000
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