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Activation of the MEK5/ERK5 Cascade Is Responsible for Biliary Dysgenesis in a Rat Model of Caroli’s Disease

Polycystic kidney (PCK) rats exhibit a multiorgan cyst pathology similar to human autosomal recessive polycystic kidney disease, and are proposed as an animal model of Caroli’s disease with congenital hepatic fibrosis (CHF). This study investigated the expression and function of selected components...

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Detalhes bibliográficos
Main Authors: Sato, Yasunori, Harada, Kenichi, Kizawa, Kazuo, Sanzen, Takahiro, Furubo, Shinichi, Yasoshima, Mitsue, Ozaki, Satoru, Ishibashi, Masahiko, Nakanuma, Yasuni
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602300/
https://ncbi.nlm.nih.gov/pubmed/15631999
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