ABCA1 Gene Deletion Protects against Cerebral Malaria: Potential Pathogenic Role of Microparticles in Neuropathology

The ATP-binding cassette transporter A1 (ABCA1) modulates the transbilayer distribution of phosphatidylserine at the outer leaflet of the plasma membrane. This external exposure of phosphatidylserine is a hallmark of microparticle production and is impaired in ABCA1(−/−) mice. In this study, we repo...

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Detalhes bibliográficos
Main Authors: Combes, Valéry, Coltel, Nicolas, Alibert, Mélanie, van Eck, Miranda, Raymond, Cécile, Juhan-Vague, Irène, Emile Grau, Georges, Chimini, Giovanna
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2005
Assuntos:
Original Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602289/
https://ncbi.nlm.nih.gov/pubmed/15632021
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