Site-Specific Expression of Polycomb-Group Genes Encoding the HPC-HPH/PRC1 Complex in Clinically Defined Primary Nodal and Cutaneous Large B-Cell Lymphomas

Polycomb-group (PcG) genes preserve cell identity by gene silencing, and contribute to regulation of lymphopoiesis and malignant transformation. We show that primary nodal large B-cell lymphomas (LBCLs), and secondary cutaneous deposits from such lymphomas, abnormally express the BMI-1, RING1, and H...

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Main Authors: Raaphorst, Frank M., Vermeer, Maarten, Fieret, Elly, Blokzijl, Tjasso, Dukers, Danny, Sewalt, Richard G.A.B., Otte, Arie P., Willemze, Rein, Meijer, Chris J.L.M.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2004
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602277/
https://ncbi.nlm.nih.gov/pubmed/14742259
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