Repair of Local Bone Erosions and Reversal of Systemic Bone Loss Upon Therapy with Anti-Tumor Necrosis Factor in Combination with Osteoprotegerin or Parathyroid Hormone in Tumor Necrosis Factor-Mediated Arthritis

Local bone erosion and systemic bone loss are hallmarks of rheumatoid arthritis and cause progressive disability. Tumor necrosis factor (TNF) is a key mediator of arthritis and acts catabolically on bone by stimulating bone resorption and inhibiting bone formation. We hypothesized that the concerted...

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Main Authors: Redlich, Kurt, Görtz, Birgit, Hayer, Silvia, Zwerina, Jochen, Doerr, Nicholas, Kostenuik, Paul, Bergmeister, Helga, Kollias, George, Steiner, Günter, Smolen, Josef S., Schett, Georg
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2004
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602264/
https://ncbi.nlm.nih.gov/pubmed/14742260
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