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Increased Expression of β6-Integrin in Skin Leads to Spontaneous Development of Chronic Wounds

Integrin αvβ6 is an epithelial cell-specific receptor that is not normally expressed by resting epithelium but its expression is induced during wound healing. The function of αvβ6-integrin in wound repair is not clear. In the present study, we showed that β6-integrin expression was strongly up-regul...

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Bibliographic Details
Main Authors: Häkkinen, Lari, Koivisto, Leeni, Gardner, Humphrey, Saarialho-Kere, Ulpu, Carroll, Joseph M., Lakso, Merja, Rauvala, Heikki, Laato, Matti, Heino, Jyrki, Larjava, Hannu
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2004
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602209/
https://ncbi.nlm.nih.gov/pubmed/14695336
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