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A protein-based therapeutic for human cytomegalovirus infection

Current antiviral strategies target viral gene products. Although initially successful, their severe toxicity and susceptibility to circumvention by the generation of drug-resistant variants limit their usefulness. By contrast, the central role of the host cell serine endoprotease furin in the prote...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Jean, François, Thomas, Laurel, Molloy, Sean S., Liu, Gseping, Jarvis, Michael A., Nelson, Jay A., Thomas, Gary
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2000
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16021/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10681468/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.050504297
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