INTERLEUKIN-4 SUPPRESSION OF INTERLEUKIN-1–INDUCED TRANSCRIPTION OF COLLAGENASE (MMP-1) AND STROMELYSIN 1 (MMP-3) IN HUMAN SYNOVIAL FIBROBLASTS

OBJECTIVE: To determine the effects of interleukin-4 (IL-4) on IL-1 induction of collagenase (matrix metalloproteinase 1 [MMP-1]) and stromelysin-1 (MMP-3) in human synovial fibroblasts. METHODS: Northern blot analysis was performed to determine the effects of IL-4 on IL-1 induction of MMP messenger...

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Main Authors: BORGHAEI, RUTH CARTER, RAWLINGS, P. LYLE, MOCHAN, EUGENE
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602062/
https://ncbi.nlm.nih.gov/pubmed/9704637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1529-0131(199808)41:8<1398::AID-ART8>3.0.CO;2-B
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