Halofuginone suppresses the lung metastasis of chemically induced hepatocellular carcinoma in rats through MMP inhibition

Halofuginone, an inhibitor of collagen synthesis, appears to be a promising antitumoral drug in preclinical studies. We used a relevant rat model of autochthonous, chemically induced, spontaneously metastasizing hepatocellular carcinoma (HCC) to test the efficacy of halofuginone on tumor progression...

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Main Authors: Taras, Danièle, Blanc, Jean-Frédéric, Rullier, Anne, Dugot-Senant, Nathalie, Laurendeau, Ingrid, Bièche, Ivan, Pines, Mark, Rosenbaum, Jean
Formáid: Artigo
Teanga:Inglês
Foilsithe: Neoplasia Press Inc. 2006
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1600678/
https://ncbi.nlm.nih.gov/pubmed/16756723
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