A B-cell receptor-specific selection step governs immature to mature B cell differentiation

Seventy percent of peripheral immature conventional (B2) B cells fail to develop into mature B cells. The nature of this cell loss has not been characterized; the process that governs which immature B cells develop into long-lived peripheral B cells could be either stochastic or selective. Here, we...

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Detalhes bibliográficos
Main Authors: Levine, Matthew H., Haberman, Ann M., Sant'Angelo, Derek B., Hannum, Lynn G., Cancro, Michael P., Janeway, Charles A., Shlomchik, Mark J.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC16000/
https://ncbi.nlm.nih.gov/pubmed/10688906
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