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Mg(2+)–RNA interaction free energies and their relationship to the folding of RNA tertiary structures

Mg(2+) ions are very effective at stabilizing tertiary structures in RNAs. In most cases, folding of an RNA is so strongly coupled to its interactions with Mg(2+) that it is difficult to separate free energies of Mg(2+)– RNA interactions from the intrinsic free energy of RNA folding. To devise quant...

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Main Authors: Grilley, Dan, Soto, Ana Maria, Draper, David E.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2006
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1599903/
https://ncbi.nlm.nih.gov/pubmed/16966612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606409103
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