The nucleotide-binding site of bacterial translation initiation factor 2 (IF2) as a metabolic sensor

Translational initiation factor 2 (IF2) is a guanine nucleotide-binding protein that can bind guanosine 3′,5′-(bis) diphosphate (ppGpp), an alarmone involved in stringent response in bacteria. In cells growing under optimal conditions, the GTP concentration is very high, and that of ppGpp very low....

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Bibliografiske detaljer
Main Authors: Milon, Pohl, Tischenko, Eugene, Tomšic, Jerneja, Caserta, Enrico, Folkers, Gert, La Teana, Anna, Rodnina, Marina V., Pon, Cynthia L., Boelens, Rolf, Gualerzi, Claudio O.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2006
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1599896/
https://ncbi.nlm.nih.gov/pubmed/16968770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606384103
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