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The nucleotide-binding site of bacterial translation initiation factor 2 (IF2) as a metabolic sensor
Translational initiation factor 2 (IF2) is a guanine nucleotide-binding protein that can bind guanosine 3′,5′-(bis) diphosphate (ppGpp), an alarmone involved in stringent response in bacteria. In cells growing under optimal conditions, the GTP concentration is very high, and that of ppGpp very low....
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1599896/ https://ncbi.nlm.nih.gov/pubmed/16968770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606384103 |
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