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All-trans retinoic acid inhibits proliferation of intestinal epithelial cells by inhibiting expression of the gene encoding Krüppel-like factor 5
Retinoids are known inhibitors of epithelial cell proliferation. Previous studies indicate that Krüppel-like factor 5 (KLF5) is a pro-proliferative transcription factor. Here, we examined the effect of all-trans retinoid acid (ATRA) on proliferation of the intestinal epithelial cell line, IEC6. Trea...
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Hauptverfasser: | , , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2004
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1599793/ https://ncbi.nlm.nih.gov/pubmed/15581624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2004.10.079 |
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