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All-trans retinoic acid inhibits proliferation of intestinal epithelial cells by inhibiting expression of the gene encoding Krüppel-like factor 5

Retinoids are known inhibitors of epithelial cell proliferation. Previous studies indicate that Krüppel-like factor 5 (KLF5) is a pro-proliferative transcription factor. Here, we examined the effect of all-trans retinoid acid (ATRA) on proliferation of the intestinal epithelial cell line, IEC6. Trea...

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Bibliographische Detailangaben
Hauptverfasser: Chanchevalap, Sengthong, Nandan, Mandayam O., Merlin, Didier, Yang, Vincent W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1599793/
https://ncbi.nlm.nih.gov/pubmed/15581624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2004.10.079
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