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Human cytomegalovirus UL69 protein is required for efficient accumulation of infected cells in the G(1) phase of the cell cycle

Human cytomegalovirus blocks cell-cycle progression in the G(1) compartment upon infection of primary human fibroblasts. The virus-coded UL69 protein can institute a G(1) block when expressed in cells in the absence of virus infection. We have constructed a cytomegalovirus mutant, TNsubUL69, that la...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hayashi, Mansuo Lu, Blankenship, Catherine, Shenk, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC15991/
https://ncbi.nlm.nih.gov/pubmed/10706637
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