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The genetics of ivermectin resistance in Caenorhabditis elegans

The ability of organisms to evolve resistance threatens the effectiveness of every antibiotic drug. We show that in the nematode Caenorhabditis elegans, simultaneous mutation of three genes, avr-14, avr-15, and glc-1, encoding glutamate-gated chloride channel (GluCl) α-type subunits confers high-lev...

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Huvudupphovsmän: Dent, Joseph A., Smith, McHardy M., Vassilatis, Demetrios K., Avery, Leon
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 2000
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC15988/
https://ncbi.nlm.nih.gov/pubmed/10716995
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