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5-Hydroxytryptamine 2B receptor regulates cell-cycle progression: Cross-talk with tyrosine kinase pathways

In this paper, we present evidence that activation of 5-hydroxytryptamine 2B (5-HT2B) receptors by serotonin (5-HT) leads to cell-cycle progression through retinoblastoma protein hyperphosphorylation and through activation of both cyclin D1/cdk4 and cyclin E/cdk2 kinases by a mechanism that depends...

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Bibliografiska uppgifter
Huvudupphovsmän: Nebigil, Canan G., Launay, Jean-Marie, Hickel, Pierre, Tournois, Claire, Maroteaux, Luc
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 2000
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC15973/
https://ncbi.nlm.nih.gov/pubmed/10688905
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