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Two ligand-binding sites in the O(2)-sensing signal transducer HemAT: Implications for ligand recognition/discrimination and signaling
We have identified a ligand (CO) accommodation cavity in the signal transducer sensor protein HemAT (heme-based aerotactic transducer) that allows us to gain single-molecule insights into the mechanism of gas sensor proteins. Specific mutations that are distal and proximal to the heme were designed...
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2006
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1595431/ https://ncbi.nlm.nih.gov/pubmed/17003124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604248103 |
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