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Genetic Evidence for an Interaction of the UbiG O-Methyltransferase with UbiX in Escherichia coli Coenzyme Q Biosynthesis

IS16 is a thiol-sensitive, Q-deficient mutant strain of Escherichia coli. Here, we show that IS16 harbors a mutation in the ubiG gene encoding a methyltransferase required for two O-methylation steps of Q biosynthesis. Complementation of IS16 with either ubiG or ubiX(K-12) reverses this phenotype, s...

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Autors principals: Gulmezian, Melissa, Zhang, Haitao, Javor, George T., Clarke, Catherine F.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1595381/
https://ncbi.nlm.nih.gov/pubmed/16923914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00668-06
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