Erythroid Krüppel-like factor is recruited to the CACCC box in the β-globin promoter but not to the CACCC box in the γ-globin promoter: The role of the neighboring promoter elements
The programmed expression of the five β-like globin genes (ɛ, (A)γ, (G)γ, δ, and β) is characterized by a series of switches that are developmentally regulated. The (A)γ- and (G)γ- (fetus) to β-globin (adult) switch depends on transcription factor erythroid Krüppel-like factor (EKLF), which, like Sp...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15952/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10706605/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.040476297 |
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