Cargando...

Erythroid Krüppel-like factor is recruited to the CACCC box in the β-globin promoter but not to the CACCC box in the γ-globin promoter: The role of the neighboring promoter elements

The programmed expression of the five β-like globin genes (ɛ, (A)γ, (G)γ, δ, and β) is characterized by a series of switches that are developmentally regulated. The (A)γ- and (G)γ- (fetus) to β-globin (adult) switch depends on transcription factor erythroid Krüppel-like factor (EKLF), which, like Sp...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Lee, Jong-Soo, Ngo, Hailong, Kim, David, Chung, Jay H.
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2000
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC15952/
https://ncbi.nlm.nih.gov/pubmed/10706605
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!