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High-Affinity Interaction between Fibronectin and the Group B Streptococcal C5a Peptidase Is Unaffected by a Naturally Occurring Four-Amino-Acid Deletion That Eliminates Peptidase Activity

The streptococcal C5a peptidase (ScpB) of group B streptococci (GBS) is found in virtually all clinical GBS isolates and is required for mucosal colonization in a neonatal mouse model. ScpB inhibits neutrophil chemotaxis by enzymatically cleaving the complement component C5a. We previously identifie...

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Bibliografiske detaljer
Main Authors: Tamura, Glen S., Hull, James R., Oberg, Michael D., Castner, David G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1594932/
https://ncbi.nlm.nih.gov/pubmed/16988251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00241-06
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