Differential Role of Lipooligosaccharide of Neisseria meningitidis in Virulence and Inflammatory Response during Respiratory Infection in Mice

Meningococcal lipooligosaccharide (LOS) induces a strong proinflammatory response in humans during meningococcal infection. We analyzed the role of LOS in the inflammatory response and virulence during the early infectious process in a mouse model of meningococcal respiratory challenge. An lpxA muta...

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Bibliografiske detaljer
Main Authors: Zarantonelli, Maria Leticia, Huerre, Michel, Taha, Muhamed-Kheir, Alonso, Jean-Michel
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
Fag:
Host Response and Inflammation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1594929/
https://ncbi.nlm.nih.gov/pubmed/16988225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00655-06
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