Fatty Acids from Plasmodium falciparum Down-Regulate the Toxic Activity of Malaria Glycosylphosphatidylinositols

Plasmodium falciparum malaria kills roughly 2.5 million people, mainly children, annually. Much of this mortality is thought to arise from the actions of a malarial toxin. This toxin, identified as glycosylphosphatidylinositol (GPI), is a major pathogenicity determinant in malaria. A malarial molecu...

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Bibliographische Detailangaben
Hauptverfasser: Debierre-Grockiego, Françoise, Schofield, Louis, Azzouz, Nahid, Schmidt, Jörg, Santos de Macedo, Cristiana, Ferguson, Michael A. J., Schwarz, Ralph T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
Schlagworte:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1594897/
https://ncbi.nlm.nih.gov/pubmed/16988223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01934-05
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