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Organ- and Disease-Stage-Specific Regulation of Toxoplasma gondii-Specific CD8-T-Cell Responses by CD4 T Cells

Toxoplasma gondii induces a persistent central nervous system infection, which may be lethally reactivated in AIDS patients with low CD4 T-cell numbers. To analyze the role of CD4 T cells for the regulation of parasite-specific CD8 T cells, mice were infected with transgenic T. gondii expressing the...

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Detalhes bibliográficos
Main Authors: Lütjen, Sonja, Soltek, Sabine, Virna, Simona, Deckert, Martina, Schlüter, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1594890/
https://ncbi.nlm.nih.gov/pubmed/16988257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00098-06
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